Isolated involvement of substantia nigra in acute transient parkinsonism: MRI and PET observations
Identifieur interne : 003F62 ( Main/Exploration ); précédent : 003F61; suivant : 003F63Isolated involvement of substantia nigra in acute transient parkinsonism: MRI and PET observations
Auteurs : Shinn-Kuang Lin [Taïwan] ; Chin-Song Lu [Taïwan] ; François Vingerhoets [Taïwan] ; Barry J. Snow [Taïwan] ; Yau-Yau Wai [Canada] ; Nai-Shin Chu [Taïwan] ; Donald B. Calne [Taïwan]Source :
- Parkinsonism and Related Disorders [ 1353-8020 ] ; 1995.
Abstract
A woman, aged 27 years, developed acute headache and fever followed by tremor, rigidity, and bradykinesia. Masked face, drooling saliva, monotonous voice, and dysphagia were observed. She was totally bedridden during the worst period because of marked generalized rigidity and bradykinesia. There was no neurological disturbance other than parkinsonism. Several herpetic vesicles were noticed at the left angle of her mouth. The cerebrospinal fluid revealed a mononuclear pleocytosis with a normal concentration of sugar and protein. The antibody test for Type I herpes simplex virus was positive in the serum but negative in the cerebrospinal fluid. Brain CT and EEG were normal. However, MRI study showed markedly increased signals in the bilateral substantia nigra on T2-weighted, proton density, and in gradient recall acquisition imagings. Those abnormal findings had almost disappeared in a follow-up MRI study 2 months later. Her parkinsonian symptoms were substantially resolved by the time. However, PET scans, performed 8 months later, disclosed: (1) mild reduction of fluorodopa uptake; and (2) increased raclopride binding, predominantly in the putamen. These findings suggest a subclinical nigrostriatal dopaminergic deficit and a relative excess of the D2 receptors, with a pattern similar to that found in typical idiopathic parkinsonism.
Url:
DOI: 10.1016/1353-8020(95)00017-8
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001889
- to stream Istex, to step Curation: 001889
- to stream Istex, to step Checkpoint: 001936
- to stream Main, to step Merge: 004684
- to stream Main, to step Curation: 003F62
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Isolated involvement of substantia nigra in acute transient parkinsonism: MRI and PET observations</title><author><name sortKey="Lin, Shinn Kuang" sort="Lin, Shinn Kuang" uniqKey="Lin S" first="Shinn-Kuang" last="Lin">Shinn-Kuang Lin</name></author><author><name sortKey="Lu, Chin Song" sort="Lu, Chin Song" uniqKey="Lu C" first="Chin-Song" last="Lu">Chin-Song Lu</name></author><author><name sortKey="Vingerhoets, Francois" sort="Vingerhoets, Francois" uniqKey="Vingerhoets F" first="François" last="Vingerhoets">François Vingerhoets</name></author><author><name sortKey="Snow, Barry J" sort="Snow, Barry J" uniqKey="Snow B" first="Barry J" last="Snow">Barry J. Snow</name></author><author><name sortKey="Wai, Yau Yau" sort="Wai, Yau Yau" uniqKey="Wai Y" first="Yau-Yau" last="Wai">Yau-Yau Wai</name></author><author><name sortKey="Chu, Nai Shin" sort="Chu, Nai Shin" uniqKey="Chu N" first="Nai-Shin" last="Chu">Nai-Shin Chu</name></author><author><name sortKey="Calne, Donald B" sort="Calne, Donald B" uniqKey="Calne D" first="Donald B" last="Calne">Donald B. Calne</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:410112EDA860FDB0A1F3ED55F57E1EDF1D4BBB5F</idno><date when="1995" year="1995">1995</date><idno type="doi">10.1016/1353-8020(95)00017-8</idno><idno type="url">https://api-v5.istex.fr/document/410112EDA860FDB0A1F3ED55F57E1EDF1D4BBB5F/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001889</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001889</idno><idno type="wicri:Area/Istex/Curation">001889</idno><idno type="wicri:Area/Istex/Checkpoint">001936</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001936</idno><idno type="wicri:doubleKey">1353-8020:1995:Lin S:isolated:involvement:of</idno><idno type="wicri:Area/Main/Merge">004684</idno><idno type="wicri:Area/Main/Curation">003F62</idno><idno type="wicri:Area/Main/Exploration">003F62</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Isolated involvement of substantia nigra in acute transient parkinsonism: MRI and PET observations</title><author><name sortKey="Lin, Shinn Kuang" sort="Lin, Shinn Kuang" uniqKey="Lin S" first="Shinn-Kuang" last="Lin">Shinn-Kuang Lin</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Neurology, Chang Gung Memorial Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Chin Song" sort="Lu, Chin Song" uniqKey="Lu C" first="Chin-Song" last="Lu">Chin-Song Lu</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Address correspondence to: Chin-Song Lu, M.D., Department of Neurology, Chang Gung Memorial Hospital, 199 Tung Hwa North Road, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Neurology, Chang Gung Memorial Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Vingerhoets, Francois" sort="Vingerhoets, Francois" uniqKey="Vingerhoets F" first="François" last="Vingerhoets">François Vingerhoets</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Radiology, Chang Gung Memorial Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Snow, Barry J" sort="Snow, Barry J" uniqKey="Snow B" first="Barry J" last="Snow">Barry J. Snow</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Radiology, Chang Gung Memorial Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Wai, Yau Yau" sort="Wai, Yau Yau" uniqKey="Wai Y" first="Yau-Yau" last="Wai">Yau-Yau Wai</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>The Neurodegenerative Disorders Centrec, Vancouver Hospital and Health Sciences Centre, University of British Columbia, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Chu, Nai Shin" sort="Chu, Nai Shin" uniqKey="Chu N" first="Nai-Shin" last="Chu">Nai-Shin Chu</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Neurology, Chang Gung Memorial Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Calne, Donald B" sort="Calne, Donald B" uniqKey="Calne D" first="Donald B" last="Calne">Donald B. Calne</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Radiology, Chang Gung Memorial Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Parkinsonism and Related Disorders</title><title level="j" type="abbrev">PRD</title><idno type="ISSN">1353-8020</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1995">1995</date><biblScope unit="volume">1</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="67">67</biblScope><biblScope unit="page" to="72">72</biblScope></imprint><idno type="ISSN">1353-8020</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1353-8020</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A woman, aged 27 years, developed acute headache and fever followed by tremor, rigidity, and bradykinesia. Masked face, drooling saliva, monotonous voice, and dysphagia were observed. She was totally bedridden during the worst period because of marked generalized rigidity and bradykinesia. There was no neurological disturbance other than parkinsonism. Several herpetic vesicles were noticed at the left angle of her mouth. The cerebrospinal fluid revealed a mononuclear pleocytosis with a normal concentration of sugar and protein. The antibody test for Type I herpes simplex virus was positive in the serum but negative in the cerebrospinal fluid. Brain CT and EEG were normal. However, MRI study showed markedly increased signals in the bilateral substantia nigra on T2-weighted, proton density, and in gradient recall acquisition imagings. Those abnormal findings had almost disappeared in a follow-up MRI study 2 months later. Her parkinsonian symptoms were substantially resolved by the time. However, PET scans, performed 8 months later, disclosed: (1) mild reduction of fluorodopa uptake; and (2) increased raclopride binding, predominantly in the putamen. These findings suggest a subclinical nigrostriatal dopaminergic deficit and a relative excess of the D2 receptors, with a pattern similar to that found in typical idiopathic parkinsonism.</div></front></TEI><affiliations><list><country><li>Canada</li><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Lin, Shinn Kuang" sort="Lin, Shinn Kuang" uniqKey="Lin S" first="Shinn-Kuang" last="Lin">Shinn-Kuang Lin</name></noRegion><name sortKey="Calne, Donald B" sort="Calne, Donald B" uniqKey="Calne D" first="Donald B" last="Calne">Donald B. Calne</name><name sortKey="Chu, Nai Shin" sort="Chu, Nai Shin" uniqKey="Chu N" first="Nai-Shin" last="Chu">Nai-Shin Chu</name><name sortKey="Lu, Chin Song" sort="Lu, Chin Song" uniqKey="Lu C" first="Chin-Song" last="Lu">Chin-Song Lu</name><name sortKey="Lu, Chin Song" sort="Lu, Chin Song" uniqKey="Lu C" first="Chin-Song" last="Lu">Chin-Song Lu</name><name sortKey="Snow, Barry J" sort="Snow, Barry J" uniqKey="Snow B" first="Barry J" last="Snow">Barry J. Snow</name><name sortKey="Vingerhoets, Francois" sort="Vingerhoets, Francois" uniqKey="Vingerhoets F" first="François" last="Vingerhoets">François Vingerhoets</name></country><country name="Canada"><noRegion><name sortKey="Wai, Yau Yau" sort="Wai, Yau Yau" uniqKey="Wai Y" first="Yau-Yau" last="Wai">Yau-Yau Wai</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003F62 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003F62 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:410112EDA860FDB0A1F3ED55F57E1EDF1D4BBB5F
|texte= Isolated involvement of substantia nigra in acute transient parkinsonism: MRI and PET observations
}}
| This area was generated with Dilib version V0.6.29. |  |